Myosin Light Chain Kinase: A Potential Target for Treatment of Inflammatory Diseases
Myosin light chain kinase (MLCK) induces contraction of the perijunctional apical actomyosin ring in response to phosphorylation of the myosin light chain.Abnormal expression of MLCK has been observed in respiratory diseases, pancreatitis, cardiovascular diseases, cancer, and inflammatory Isolator bowel disease.The signaling pathways involved in ML